产品货号:
Z18506
中文名称:
ING4抗体
英文名称:
Anti-ING4 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ING4 Antibody |
指标别名 | ING4;Inhibitor of growth protein 4;my036;p29ING4 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | ING4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from the Internal region of human ING4. |
计算分子量 | 29KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | Immunogen affinity purified |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | p29 ING4 is a tumor suppressor protein similar to ING1 that may inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation.p29 ING4 has been shown to suppress brain tumor angio-genesis through transcriptional repression of RelA/NFKB3 target genes when complexed with RelA.p29 ING4 may also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC.p29 ING4 shows a nuclear localization and interacts with EP300,TP53,RelA,inhibits cell growth,and induces apoptosis.This protein contains a PHD-finger,which is a common motif in proteins involved in chromatin remodeling.Multiple alternatively spliced transcript variants have been observed.The accession number listed below is for variant (1) that encodes the longest isoform. |
Uniprot ID | Q9UNL4 |
基因名全称 | Inhibitor of growth protein 4 |
推荐稀释比 | WB,1:500~1:2000 |
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